What is Albumin?

 

Serum Albumin is the most abundant protein found in human blood plasma. Its a large "heart-shaped" protein of high molecular weight which is produced by the liver.  In the circulatory system it plays a vital role in the maintenance of osmotic blood pressure and blood pH.  Albumin also plays an essential role in the transport, distribution and metabolism of a broad array of ligands including many of the most important pharmaceuticals on the market today. It is in effect, Mother Nature's drug delivery system.  Drug affinity and binding location to albumin can significantly alter the half-life, distribution and metabolism of drugs, thereby playing a major role in the ADME (absorption, distribution, metabolism and secretion) of many important pharmaceuticals.This same binding function also imparts a protection from harmful metabolc products and environmental exposures.

 

Albumin Applications:

Because of albumin's abundance, purity, and special properties, like chemical binding and stabilzing affects, it has been used successfully and to advantage in numerous applications.  More recent availability of recombinant albumin (eg. Albumin Bioscience) which avoids the risks from animal derived materials, has expanded the number of new applications